What is the adult dosing for Promethazine?

The adult dosing for Promethazine is typically 6.25mg per dose, with a total maximum dose of 12.5mg. This dosing regimen is commonly adopted because it strikes a balance between efficacy and safety when managing conditions such as nausea, vomiting, or motion sickness.

Promethazine is an antiemetic that works by blocking histamine receptors in the brain, helping to alleviate symptoms of nausea and preventing vomiting. The 6.25mg dose is effective for most adults while reducing the risk of side effects. Exceeding the total maximum dose can lead to increased adverse reactions, which is why the upper limit of 12.5mg is established.

The other doses presented do not align with the typical practices and established guidelines for Promethazine dosing, making them less appropriate for standard adult administration.