What condition results from a significant loss of body fluids?

The condition that results from a significant loss of body fluids is dehydration. Dehydration occurs when the body does not have enough water and other fluids to carry out its normal functions. This can happen due to various reasons such as excessive sweating, vomiting, diarrhea, or inadequate fluid intake. When the body loses fluids, it can lead to an imbalance in electrolytes, affecting organ function and overall health.

In contrast, hypervolemia refers to an excess of fluid in the body, which is the opposite of dehydration. Sepsis is a severe response to infection that can cause widespread inflammation and organ dysfunction, but it does not directly relate to the loss of body fluids. Hypotension, which is low blood pressure, can result from dehydration but is a symptom rather than a condition caused by fluid loss. Thus, dehydration is the most accurate answer in this context.